Urea synthesis

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Urea synthesis by liver homogenates.

The synthesis of citrulline from ornithine and arginine from citrulline has heretofore been associated only with intact liver cells. In the course of studies on the mechanism of the conversion of citrulline to a&nine, a highly active system was found in liver homogenate capable of forming urea in the presence of glutamic acid, adenosine triphosphate (ATP), cytochrome c, an oxygen atmosphere, an...

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Urea Synthesis by Hemic Cells.

A method for measuring urea production by isolated erythrocytes and leucocytes under physiologic conditions is described. Erythrocytes from 10 normal subjects formed an average of 82.5 mmoles urea/mi. packed cells/hr. Leucocytes formed 7.4 mmoles urea/108 cells/hr. By extrapolation, total urea synthesis by circulating erythrocytes would be approximately 270 mg./day and by the granulocyte pool a...

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Urea Synthesis in Novikoff and Morris Hepatomas1

found that N-acetyl-L-glutamate-dependent CPS l@ EEC 2.7.2.5 (NH4)], one of the 1st steps in the pathway of urea synthesis, was retained in varying degrees in welland highly differentiated tumors (14). There was also a marked lowering of CPS I activity in the livers of rats bearing large, slow-growing tumors with high CPS I activity (21, 28A, 44, 47C, and 5123C). These findings confirm and exte...

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Structure formation in urea-formaldehyde resin synthesis

The structure formation in acid promoted polycondensation and particularly in alkaline post-treatment with urea was studied by 13C NMR spectroscopy in the three-step synthesis of ureaformaldehyde resins. Trishydroxymethyl urea was identified as the constituent of the mixture of hydroxylmethylated urea derivatives obtained in alkaline conditions. The formation of methylenes linked to secondary o...

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The enzymatic steps in urea synthesis.

lnvestigations on the synthesis of arginine from citrulline (Step II of the Krebs-Henseleit urea cycle) and citrulline from ornithine (Step I) by rat liver homogenates have been reported previously (l-3). The study of the latter reaction was made possible by the apparently critical magnesium ion concentration required for the function of the liver transimination (citrulline to arginine) system....

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ژورنال

عنوان ژورنال: Reactome - a curated knowledgebase of biological pathways

سال: 2003

ISSN: 1934-1792

DOI: 10.3180/react_847.1